PhD Candidate • Harvard-MIT Health Sciences and Technology
Group: Computer Science and Artificial Intelligence Laboratory
Advisor: Dr. Polina Golland
I am a third-year PhD candidate in Medical Engineering and Medical Physics at MIT. Motivated by unmet clinical needs, my research develops machine learning methods that deepen our ability to understand and treat diseases.
Research
Differentiable Rendering + Minimally Invasive Surgery
Intraoperative 2D/3D Image Registration via Differentiable X-ray Rendering
CVPR, 2024
We use X-ray renderering to develop DiffPose, a self-supervised framework for differentiable 2D/3D image registration that achieves sub-millimeter registration accuracy.
MICCAI Clinical Image-based Procedures Workshop, 2022
We present DiffDRR, a differentiable X-ray renderer that can be used to solve inverse problems in X-ray imaging with deep learning (e.g., registration or reconstruction).
Drug Discovery
Learning Interpretable Single-Cell Morphological Profiles from 3D Cell Painting Images
CVPRW, 2024
Society of Biomolecular Imaging and Informatics, 2023 (President's Innovation Award)
Supervised deep learning models are used ubiquitously throughout image-based drug discovery. We discover a mechanism by which these models cheat and propose an interpretability metric to quantify the level of confounding.
Statistical Graph Theory
Multiscale Comparative Connectomics
arXiv, 2021
We introduce a set of multiscale hypothesis tests to facilitate the robust and reproducible discovery of hierarchical brain structures that vary in relation with phenotypic profiles.
Annual Review of Statistics and Its Application, 2021
From a statistical graph theory perspective, we review models, assumptions, problems, and applications that are theoretically and empirically justified for analysis of connectome data.